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Crosslistings: MB&B 386 |
This course is addressed to undergraduate and graduate students interested in biological chemistry and structural biology. The course presents thermodynamic methods currently used to relate structure to function in biological molecules. Topics include: binding curves, chemical ligand linkages, binding polynomial, cooperativity, site-specific binding processes and allosteric effects. Several models for allosteric systems, such as the Monod-Wyman-Changeux model, the induced-fit model and the Pauling model are analyzed in detail. Applications of these models are illustrated for functional regulation of respiratory proteins and for protein-nucleic acid complexes involved in control of gene expression.
Unless preregistered students attend the first class meeting or communicate directly with the instructor prior to the first class, they will be dropped from the class list. NOTE: Students must still submit a completed
Drop/Add form to the Registrar's
Office.
The instructor of this course will not be using the on-line wait list. If you are interested in this course, please contact the instructor directly.
COURSE FORMAT: Lecture/Discussion
Level: UGRD Credit: 1 Gen Ed Area Dept: NONE Grading Mode: Student Option
Prerequisites: (MATH122 AND MATH122 AND CHEM381) OR (MATH121 AND MATH122 AND MB&B381)
Last Updated on MAR-18-2003
Copyright Wesleyan University, Middletown, Connecticut, 06459