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This is a 1/2 semester course (Tuesday, September 13, thru Tuesday October 25). Discussion of topics in the regulation of eukaryotic gene expression such as: Transcription factors and their mode of action; enhancers; silencers; locus control region and insulators; and the role of nucleosome positioning and chromatin structure. In addition, several illuminating systems such as the response to steroid hormones or heat shock; the control of yeast mating type; muscle differentiation and MyoD; and homeoproteins in development will be examined. Control of gene expression by RNA processing, stability or translation will be briefly considered. Emphasis throughout the course will be placed on the experimental methods that have given us our current understanding of the regulation of gene expression.
COURSE FORMAT: Lecture
Level: GRAD Credit: .5 Gen Ed Area Dept: NONE Grading Mode: Student Option
Prerequisites: MB&B208
Last Updated on MAR-24-2000
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