This course will examine multiple processes through which the primary information derived from DNA is regulated and utilized by cells. Included will be topics such as RNA processing, editing, splicing, transport, activation, translation and degradation. The regulation of such posttranscriptional processes is critically important for cellular maintenance and activity; and alterations of them provides the bases of action for certain hormones and viruses. The influence of these processes on cell growth-division, cellular differentiation, normal embryonic development and carcinogenesis will be a major consideration. Enzymatically active RNAs (ribozymes) will be considered within the evolutionary model that hypothsizes a prior RNA-based World.
COURSE FORMAT: Lecture
Level: UGRD Credit: 1 Gen Ed Area Dept: NSM MOBB Grading Mode: Graded
Prerequisites: MB&B208
Last Updated on MAR-24-2000
Copyright Wesleyan University, Middletown, Connecticut, 06459