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MB&B524
Molecular Processes in Post-Transcriptional Regulation of Gene Activity
MB&B524 SP
Not Currently Offered
This course will examine multiple processes through which
the primary information derived from DNA is regulated and
utilized by cells. Included will be topics such as RNA
processing, editing, splicing, transport, activation,
translation and degradation. The regulation of such
post-transcriptional processes is critically important for
cellular maintenance and activity; and alterations of them
provides the bases of action for certain hormones and
viruses. The influence of these processes on cell
growth-division, cellular differentiation, normal embryonic
development and carcinogenesis will be a major
consideration. Enzymatically active RNAs (ribozymes) will be
considered within the evolutionary model that hypothsizes a
prior "RNA-based World".
MAJOR READINGS
Readings will be of articles from such
journals as; Cell, Nature, Science, Genes & Development,
Journal of Biochemistry. And from reviews in TIBS, and
Genetics.
EXAMINATIONS AND ASSIGNMENTS
The course will have a final
(take-home) exam and either a written assignment or a
mid-term (take-home) exam.
ADDITIONAL REQUIREMENTS and/or COMMENTS
Prerequisite
MB&B208 or permission of instructor.
Unless preregistered students attend the first class meeting
or communicate directly with the instructor prior to the
first class, they will be dropped from the class list.
NOTE: Students must still submit a completed Drop/Add form
to the Registrar's Office.
COURSE FORMAT: Lecture
REGISTRATION INFORMATION
Level: GR Credit: 1.00
Prerequisites:
MB&B208
Last Updated on MAR-22-1999
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Copyright Wesleyan University, Middletown, Connecticut, 06459