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CHEM505

Biological Molecules
CHEM505 FA

Crosslistings: MB&B505

Not Currently Offered

An interdisciplinary approach to the investigation of a series of biological molecules with an emphasis on structure and interactions of proteins and nucleic acids. The course begins with an elementary introduction to the structure and morphology of polypeptides and oligonucleotides, and techniques for structural studies including X-ray crystallography, nuclear magnetic resonance spectroscopy and molecular dynamics calculations. The structure of a series of biological molecules of both historical and contemporary interest is then considered. Implications of the structural information in the development of modern biological chemistry and molecular biology will be considered. The material will be readily accessible to biology, chemistry, molecular biology and physics majors.

MAJOR READINGS

Schulz & Shirmer, PRINCIPLES OF PROTEIN
STRUCTURE
Saenger, PRINCIPLES OF NUCLEIC ACID STRUCTURE
McCammon & Harvey, DYNAMICS OF PROTEINS AND NUCLEIC ACIDS

EXAMINATIONS AND ASSIGNMENTS

One classroom presentation and one term project, final examination

ADDITIONAL REQUIREMENTS and/or COMMENTS

This course is essentially identical with CHEM301.

COURSE FORMAT: Discussion Lecture Workshop

REGISTRATION INFORMATION

Level: GR Credit: 1.00

Prerequisites: None

Last Updated on MAR-22-1999




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