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MB&B523

Energetics and Mechanisms of Protein-Nucleic Acids
MB&B523 FA

Crosslistings: CHEM590

Next Offered in 9899 FA

Interactions This course focuses on the recent advances in our understanding of the biophysical basis of protein-nucleic acid interactions. Topics will include informational and mechanistic aspects of nucleic acids recognition by proteins, the statistical thermodynamics of molecular switches in gene expression, and complementarity and intermolecular contacts in protein-nucleic acid complexes. The course aims at providing a coherent physical framework for current developments in molecular biology and related fields.

MAJOR READINGS

Journals: Proceedings of the National
Academy of Sciences, USA; Biochemistry; Cell; Quarterly
Reviews of Biophysics; Nature and Science

EXAMINATIONS AND ASSIGNMENTS

One midterm, one final (3 hours), one paper presentation.

ADDITIONAL REQUIREMENTS and/or COMMENTS

COURSE FORMAT: Discussion Lecture Seminar

REGISTRATION INFORMATION

Level: GR Credit: 1.00

Prerequisites: None

Last Updated on MAR-10-1997




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