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Academic Year 2005/2006

Structure-Function and Kinetics of DNA Metabolic Enzymes
MB&B 532 SP
Crosslistings:
MB&B 332

The key to understanding how enzyme catalysts work is to understand their structure and properties, and the kinetics and thermodynamics of their reactions. In this course you will learn how the principles of kinetics and thermodynamics are used to investigate the mechanisms of action of these biological machines. The focus, in particular, will be on learning the workings of enzymes responsible for DNA replication, repair, and recombination.

MAJOR READINGS

Alan Fersht, STRUCTURE AND MECHANISM IN PROTEIN SCIENCE
H. Gutfreund, KINETICS FOR THE LIFE SCIENCES

EXAMINATIONS AND ASSIGNMENTS

Problem sets. One midterm, one final.

COURSE FORMAT: Lecture/Discussion

REGISTRATION INFORMATION

Level: GRAD    Credit: .5    Gen Ed Area Dept: NONE    Grading Mode: Graded   

Prerequisites: NONE Links to Web Resources For This Course.

Last Updated on MAR-30-2006

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