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Academic Year 2005/2006

Molecular, Proteomic and Cell Biological Analysis of Telomere Composition and Function
MB&B 513 FA

This course will focus on a critical feature of the eukaryotic cell known as the telomere, or linear chromosome end. We will discuss the diverse set of critical molecular mechanisms affected by and involving telomeres including chromosome segregation, cellular aging, meiotic gamete production, and cancer progression. We will also focus on the physical architecture of the telomere, how this architecture dynamically alters in different biological contexts, and the types of molecules known to associate with telomeres in multiple model organisms including yeast and human cells. An emphasis will be placed on experimental strategies used for identifying new components of the telomere complex and for understanding telomere function during normal and diseased cellular states.

MAJOR READINGS

EXAMINATIONS AND ASSIGNMENTS

ADDITIONAL REQUIREMENTS and/or COMMENTS

COURSE FORMAT: Lecture

REGISTRATION INFORMATION

Level: GRAD    Credit: .5    Gen Ed Area Dept: NSM MB&B    Grading Mode: Graded   

Prerequisites: NONE

SECTION 01

Instructor(s): Flory,Mark Randall   

Times: ..T.R.. 10:30AM-11:50AM;     Location: SHAN201;

Reserved Seats:    (Total Limit: UNL)

Special Attributes:

Last Updated on MAR-30-2006

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