MB&B305 - Mechanisms of DNA Damge/Repair and Related Diseases

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Academic Year 2005/2006

Mechanisms of DNA Damge/Repair and Related Diseases
MB&B 305 SP

Crosslistings:
MB&B 505

Students taking this course will learn about the sources and consequences of DNA damage and about the biological processes dedicated to DNA repair in prokaryotes and eukaryotes, including humans. Substantial attention will be paid to current research in the DNA repair and mutagenesis field, including biochemical and biophysical approaches aimed at understanding the molecular mechanisms of DNA repair and the diseases associated with defective repair mechanisms. In this context, we will also discuss methodology used to study the workings of biological catalysts.

MAJOR READINGS

Errol C. Friedberg, Graham C. Walker, Wolfram Siede, Richard D. Wood, Roger A. Schultz, Tom Ellenberger, DNA REPAIR AND MUTAGENESIS, 2nd edition (ASM Press, 2005)
Research articles from journals such as Science, Nature, PNAS USA, Cell, EMBO J, Molecular Cell, etc.

EXAMINATIONS AND ASSIGNMENTS

In-class participation, one or two mid term exams and a final exam (possibly take-home), as well as a few short problem-solving/essay assignments.

ADDITIONAL REQUIREMENTS and/or COMMENTS

This course is designed for science graduate students and majors, however any student with interest in/some knowledge of life science disciplines and willing to work at learning the material is welcome.

COURSE FORMAT: Lecture/Discussion

REGISTRATION INFORMATION

Level: UGRD Credit: 1 Gen Ed Area Dept: NSM MB&B Grading Mode: Graded

Prerequisites: NONE

SECTION 01

Instructor(s): Hingorani,Manju

Times: .M.W... 06:10PM-07:30PM; Location: HALL230;

Reserved Seats: (Total Limit: 40)

SR. major: 10 Jr. major: 10

SR. non-major: 0 Jr. non-major: 0 SO: 10 FR: X

Special Attributes:

Links to Web Resources For This Course.

Last Updated on MAR-30-2006