CHEM325 - Introduction to Biomolecular Structure

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Academic Year 2005/2006

Introduction to Biomolecular Structure
CHEM 325 SP

Crosslistings:
MB&B 325

This course aims at providing a framework for understanding three-dimensional structures of proteins, nucleic acids and their complexes. The first half of the course emphasizes structural modules and topological patterns in major classes of proteins and nucleic acids. The second part of the course covers novel structural motifs, such as helix-turn-helix, zinc-finger and leucine zipper, which are responsible for recognition of specific nucleotide sequences in nucleic acids by proteins. Analysis of structures using tools available on the web and independent exploration of protein and nucleic acid databases are strongly encouraged.

MAJOR READINGS

Branden and Tooze, INTRODUCTION TO PROTEIN STRUCTURE
Selected journal articles.

EXAMINATIONS AND ASSIGNMENTS

Two midterm exams and final exam

ADDITIONAL REQUIREMENTS and/or COMMENTS

Prerequisite can be an equivalent course to MB&B/BIOL 181. This course is recommended for all students interested in structural biology, especially those majoring in biological chemistry, molecular biology and biochemistry, and molecular biophysics.

COURSE FORMAT: Lecture/Discussion

REGISTRATION INFORMATION

Level: UGRD Credit: 1 Gen Ed Area Dept: NONE Grading Mode: Student Option

Prerequisites: [MB&B181 or BIOL181]

SECTION 01

Instructor(s): Russu,Irina M.

Times: ..T.R.. 10:30AM-11:50AM; Location: SCIE58;

Reserved Seats: (Total Limit: UNL)

Special Attributes:

Curricular Renewal: Quantitative Reasoning

Links to Web Resources For This Course.

Last Updated on MAR-30-2006