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Academic Year 2004/2005

Energetics and Mechanisms of Protein-Nucleic Acids Interactions
CHEM 523 FA
Crosslistings:
MB&B 523

This course focuses on the recent advances in our understanding of the biophysical basis of protein-nucleic acid interactions. Topics will include informational and mechanistic aspects of nucleic acids recognition by proteins, the statistical thermodynamics of molecular switches in gene expression, and complementarity and intermolecular contacts in protein-nucleic acid complexes. The course aims at providing a coherent physical framework for current developments in molecular biology and related fields.

MAJOR READINGS

Journals: Proceedings of the National Academy of Sciences, USA; Biochemistry; Cell; Molecular Biology.

EXAMINATIONS AND ASSIGNMENTS

One midterm, one final (3 hours), two papers.

COURSE FORMAT: Lecture

REGISTRATION INFORMATION

Level: GRAD    Credit: 1    Gen Ed Area Dept: NONE    Grading Mode: Student Option   

Prerequisites: NONE Links to Web Resources For This Course.

Last Updated on MAR-21-2005

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