[ Wesleyan Home Page ] [ WesMaps Home Page ] [ WesMaps Archive ] [ Course Search ] [ Course Search by CID ]
Academic Year 2003/2004

Introduction to Biomolecular Structure
CHEM 325 SP
Crosslistings:
MB&B 325

This course aims at providing a framework for understanding three-dimensional structures of proteins, nucleic acids and their complexes. The first half of the course emphasizes structural modules and topological patterns in major classes of proteins and nucleic acids. The second part of the course covers novel structural motifs, such as helix-turn-helix, zinc-finger and leucine zipper, which are responsible for recognition of specific nucleotide sequences in nucleic acids by proteins. Analysis of structures using tools available on the web and independent exploration of protein and nucleic acid databases are strongly encouraged.

MAJOR READINGS

Branden and Tooze, INTRODUCTION TO PROTEIN STRUCTURE
Selected journal articles.

EXAMINATIONS AND ASSIGNMENTS

One midterm exam and final exam
Homework assignments

ADDITIONAL REQUIREMENTS and/or COMMENTS

This course will be offered the first half of the semester. Prerequisite can be an equivalent course to MB&B205. This course is recommended for all students interested in structural biology, especially those majoring in biological chemistry, molecular biology and biochemistry, and molecular biophysics.

COURSE FORMAT: Lecture/Discussion

REGISTRATION INFORMATION

Level: UGRD    Credit: .5    Gen Ed Area Dept: NONE    Grading Mode: Student Option   

Prerequisites: MB&B205 Links to Web Resources For This Course.

Last Updated on MAR-19-2004

Contact wesmaps@wesleyan.edu to submit comments or suggestions. Please include a url, course title, faculty name or other page reference in your email

Copyright Wesleyan University, Middletown, Connecticut, 06459