CHEM519 - Structural Mechanisms of Protein-Nucleic Acid Interactions

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Academic Year 2001/2002

Structural Mechanisms of Protein-Nucleic Acid Interactions
CHEM 519 SP

Crosslistings:
MB&B 519

Students have five days after the first day of class to add this course. This course focuses on the thermodynamics of binding proteins, drugs and other ligands to nucleic acids. Topics include cooperativity in binding of proteins to DNA, statistical thermodynamics of molecular switches in gene regulation, energetic linkages in binding of ligands to nucleic acids. The relationships between thermodynamics of protein-nucleic acid interactions and molecular mechanisms of gene expression are emphasized.

MAJOR READINGS

Selected papers from scientific journals.

EXAMINATIONS AND ASSIGNMENTS

Homework assignments and final exam.

ADDITIONAL REQUIREMENTS and/or COMMENTS

This course will be offered the second half of the semester.

COURSE FORMAT: Lecture

REGISTRATION INFORMATION

Level: GRAD Credit: .5 Gen Ed Area Dept: NONE Grading Mode: Student Option

Prerequisites: NONE

SECTION 01

Instructor(s): Russu,Irina M.

Times: .M...F. 01:10PM-02:30PM; Location: SCIE109

Reserved Seats: (Total Limit: UNL)

SR. major: Jr. major:

SR. non-major: Jr. non-major: SO: FR:

Special Attributes:

Links to Web Resources For This Course.

Last Updated on MAR-19-2002