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Academic Year 2000/2001


Introduction to Biomolecular Structure
CHEM 245 SP

Crosslistings:
MB&B 245

This course aims at providing a framework for understanding three-dimensional structures of proteins, nucleic acids and their complexes. The first half of the course emphasizes structural modules and topological patterns in major classes of proteins and nucleic acids. The second part of the course covers novel structural motifs, such as helix-turn-helix, zinc-finger and leucine zipper, which are responsible for recognition of specific nucleotide sequences in nucleic acids by proteins. Analysis of structures using tools available on the web and independent exploration of protein and nucleic acid databases are strongly encouraged.

MAJOR READINGS

Branden and Tooze, INTRODUCTION TO PROTEIN STRUCTURE
Selected journal articles.

EXAMINATIONS AND ASSIGNMENTS

One midterm exam and final exam
Homework assignments

ADDITIONAL REQUIREMENTS and/or COMMENTS

Prerequisite can be an equivalent course to MB&B205. This course is recommended for all students interested in structural biology, especially those majoring in biological chemistry, molecular biology and biochemistry, and molecular biophysics.

Unless preregistered students attend the first class meeting or communicate directly with the instructor prior to the first class, they will be dropped from the class list. NOTE: Students must still submit a completed Drop/Add form to the Registrar's Office.

COURSE FORMAT: Lecture/Discussion

REGISTRATION INFORMATION

Level: UGRD    Credit: .5    Gen Ed Area Dept: NONE    Grading Mode: Graded   

Prerequisites: MB&B205

SECTION 01

Instructor(s): Russu,Irina   
Times: ..T.T.. 02:40AM-04:00PM;     Location: SHAN201
Reserved Seats:    (Total Limit: UNL)
SR. major:    Jr. major:
SR. non-major:    Jr. non-major:    SO:    FR:

Special Attributes:
Curricular Renewal:    Reading Non-Verbal Texts, Speaking
Links to Web Resources For This Course.

Last Updated on MAR-26-2001


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